ea0049gp47 | Bone & Calcium Homeostasis 2 | ECE2017
Clarke Bart L
, Vokes Tamara J
, Bilezikian John P
, Bone Henry G
, Denham Douglas S
, Lee Hak-Myung
, Levine Michael A
, Mannstadt Michael
, Peacock Munro
, Rothman Jeffrey G
, Shoback Dolores M
, Warren Mark L
, Watts Nelson B
, Krasner Alan
Hypoparathyroidism (HPT) is characterised by hypocalcaemia and impaired renal phosphate excretion and calcium conservation. Oral calcium supplements and calcitriol can improve serum calcium levels but lack the physiologic effects of PTH on renal reabsorption of calcium. RACE is an ongoing open-label study evaluating the long-term safety of recombinant human parathyroid hormone 1-84 (rhPTH[1-84], parathyroid hormone rDNA) in adults with HPT (NCT01297309). In this interim analys...